Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAT1 | O14929 | 1/20 | 0.36 |
| ▸ | KAT7 | O95251 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13273926 | 0.87 | HAT1 (0.39) | HAT1KAT7EP300RBBP7CREBBP | |
| SCHEMBL12210155 | 0.86 | HAT1 (0.36) | HAT1KAT7EP300RBBP7CREBBP | |
| SCHEMBL12210494 | 0.81 | KDM4E (0.41) | KDM4EVDRALDH1A1MEN1TSHR | |
| SCHEMBL13273928 | 0.79 | HSP90AA1 (0.37) | HAT1KAT7EP300RBBP7CREBBP | |
| SCHEMBL18404401 | 0.79 | LMNA (0.41) | HAT1KAT7EP300RBBP7CREBBP | |
| SCHEMBL15060795 | 0.78 | MTNR1A (0.34) | HAT1KAT7EP300RBBP7CREBBP | |
| SCHEMBL13274128 | 0.77 | KDM4E (0.45) | KDM4EVDRALDH1A1MEN1TSHR | |
| SCHEMBL15060782 | 0.76 | KDM4E (0.35) | KDM4EVDRALDH1A1MEN1TSHR | |
| SCHEMBL15060752 | 0.76 | KDM4E (0.41) | KDM4EVDRMAPTALDH1A1MEN1 | |
| SCHEMBL15060828 | 0.76 | KDM4E (0.41) | KDM4EVDRALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074193-A1 | NOVEL BICYCLIC HETEROCYCLIC COMPOUND | 大日本住友製薬株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |