Sugi Predict

Sugi Predict / Compounds / SCHEMBL13275751

SCHEMBL13275751

SCHEMBL13275751

C[C@@H]1C=C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ CA2 P00918 8/20 0.43
▸ CA1 P00915 8/20 0.43
▸ CA12 O43570 6/20 0.43
▸ CA9 Q16790 4/20 0.43
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ TSHR P16473 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ CA4 P22748 2/20 0.31
▸ CA5A P35218 2/20 0.31
▸ CA7 P43166 2/20 0.31
▸ CA5B Q9Y2D0 2/20 0.31
▸ LGALS1 P09382 2/20 0.30
▸ LGALS3 P17931 2/20 0.30
▸ LGALS9 O00182 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1686164 0.76 CA2 (0.46) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL12563499 0.76 CA2 (0.46) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL8199560 0.76 CA2 (0.46) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL7148945 0.76 CA2 (0.46) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL18536440 0.73 CA2 (0.43) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL10955099 0.72 CA1 (0.41) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL13895535 0.72 CA1 (0.41) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL14428819 0.72 ALDH1A1 (0.37) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL9862748 0.72 CA1 (0.41) ALDH1A1HSD17B10CA2CA1CA12
SCHEMBL7155112 0.72 CA1 (0.41) ALDH1A1HSD17B10CA2CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545685-B2 Dispiropyrrolidine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2026-02-10 — — US disclosed
US-20240246989-A1 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-07-25 — — US disclosed
US-20220106324-A1 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-04-07 — — US disclosed
US-20220106324-A1 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-04-07 — — US disclosed
EP-2684880-B1 DISPIROPYRROLIDINE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2018-02-28 — — EP disclosed
US-20140121196-A1 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-05-01 — — US disclosed
US-20140121196-A1 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-05-01 — — US disclosed
US-20140121196-A1 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-05-01 — — US disclosed
EP-2684880-A1 DISPIROPYRROLIDINE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-01-15 — — EP disclosed
EP-2684880-A1 DISPIROPYRROLIDINE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-01-15 — — EP disclosed
US-8629133-B2 Dispiropyrrolidine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-01-14 — — US disclosed
US-8629133-B2 Dispiropyrrolidine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-01-14 — — US disclosed
US-8629133-B2 Dispiropyrrolidine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-01-14 — — US disclosed
US-20130165424-A9 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-27 — — US disclosed
US-20130165424-A9 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-27 — — US disclosed
US-20130165424-A9 DISPIROPYRROLIDINE DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-27 — — US disclosed
US-20120264738-A1 DISPIROPYRROLIDINE DERIVATIVES SUGIMOTO YUUICHI (JP) 2012-10-18 — — US disclosed
US-20120264738-A1 DISPIROPYRROLIDINE DERIVATIVES SUGIMOTO YUUICHI (JP) 2012-10-18 — — US disclosed
US-20120264738-A1 DISPIROPYRROLIDINE DERIVATIVES SUGIMOTO YUUICHI (JP) 2012-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264738-A1 DISPIROPYRROLIDINE DERIVATIVES MDM2, TP53, TP53BP1 ALDH1A1 1254/4885HSD17B10 2944/4885CA2 2729/4885
US-12545685-B2 Dispiropyrrolidine derivatives TP53, MDM2, TP53BP1 ALDH1A1 2383/4885HSD17B10 2895/4885CA2 3132/4885
US-20140121196-A1 DISPIROPYRROLIDINE DERIVATIVES MDM2, TP53, TPD52L2 ALDH1A1 1173/4885HSD17B10 2813/4885CA2 2287/4885
US-20240246989-A1 DISPIROPYRROLIDINE DERIVATIVES MDM2, TP53, TP53BP1 ALDH1A1 1254/4885HSD17B10 2944/4885CA2 2729/4885
US-20130165424-A9 DISPIROPYRROLIDINE DERIVATIVES MDM2, TP53, TP53BP1 ALDH1A1 1254/4885HSD17B10 2944/4885CA2 2729/4885
US-20220106324-A1 DISPIROPYRROLIDINE DERIVATIVES MDM2, TP53, TP53BP1 ALDH1A1 1254/4885HSD17B10 2944/4885CA2 2729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.