SCHEMBL13276170

SCHEMBL13276170

Cc1ccc(NN=C2C(=O)C(C(=O)O)=Cc3ccccc32)c(S(=O)(=O)O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ALDH1A1 P00352 6/20 0.35
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
GAA P10253 4/20 0.35
MAPT P10636 4/20 0.35
POLB P06746 4/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
METAP2 P50579 1/20 0.35
RECQL P46063 1/20 0.35
CASP6 P55212 1/20 0.35
ELAVL1 Q15717 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RAB9A P51151 4/20 0.34
NPC1 O15118 2/20 0.34
HPGD P15428 2/20 0.33
HSD17B10 Q99714 1/20 0.33
APAF1 O14727 3/20 0.33
TDP2 O95551 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10087038 1.00 LMNA (0.38) LMNAALDH1A1KMT2AMEN1GAA
SCHEMBL13276169 1.00 LMNA (0.38) LMNAALDH1A1KMT2AMEN1GAA
SCHEMBL14003457 0.92 LMNA (0.38) LMNAALDH1A1KMT2AMEN1GAA
SCHEMBL15113004 0.87 MAPT (0.47) LMNAALDH1A1KMT2AMEN1GAA
SCHEMBL21436650 0.84 MEN1 (0.34) LMNAALDH1A1KMT2AMEN1GAA
SCHEMBL341437 0.82 P2RY4 (0.38) ALDH1A1KMT2AMEN1GAAMAPT
SCHEMBL341670 0.82 P2RY4 (0.36) ALDH1A1KMT2AMEN1GAAMAPT
SCHEMBL9107772 0.82 P2RY4 (0.36) ALDH1A1KMT2AMEN1GAAMAPT
SCHEMBL10053800 0.81 METAP2 (0.36) LMNAALDH1A1KMT2AMEN1GAA
SCHEMBL21436560 0.81 P2RY4 (0.36) ALDH1A1KMT2AMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846014-B2 Makeup composition comprising a black colour mixture of pigments LVMH RECHERCHE (FR) 2014-09-30 US disclosed
US-8758732-B2 Makeup composition comprising a black colour mixture of pigments LVHM RECHERCHE (FR) 2014-06-24 US disclosed
US-20140140943-A1 MAKEUP COMPOSITION COMPRISING A BLACK COLOUR MIXTURE OF PIGMENTS LVMH RECHERCHE (FR) 2014-05-22 US disclosed
US-8579428-B2 Colorants XEROX CORPORATION (US) 2013-11-12 US disclosed
US-20130184388-A1 Colorants XEROX CORPORATION (US) 2013-07-18 US disclosed
US-20120263767-A1 MAKEUP COMPOSITION COMPRISING A BLACK COLOUR MIXTURE OF PIGMENTS LVMH RECHERCHE (FR) 2012-10-18 US disclosed