Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | DDT | P30046 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222012 | 0.91 | SCD (0.49) | SCDDDTDCTPP1 | |
| SCHEMBL13282224 | 0.90 | SCD (0.49) | SCDGPR119DDTDCTPP1 | |
| SCHEMBL13282171 | 0.89 | SCD (0.44) | SCDGPR119 | |
| SCHEMBL3469839 | 0.87 | DDT (0.51) | SCDGPR119DDTDCTPP1 | |
| SCHEMBL1222319 | 0.85 | SCD (0.49) | SCDDCTPP1 | |
| SCHEMBL13287208 | 0.85 | SCD (0.48) | SCDDCTPP1 | |
| SCHEMBL3477003 | 0.84 | RBP4 (0.46) | SCDDCTPP1 | |
| SCHEMBL13287226 | 0.84 | SCD (0.47) | SCDDCTPP1 | |
| SCHEMBL13282391 | 0.83 | SCD (0.47) | SCDDCTPP1 | |
| SCHEMBL13282380 | 0.82 | POLB (0.39) | DDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075356-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-01 | — | — | WO | disclosed |
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-24 | — | — | US | disclosed |
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160323-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | SCD 1/4885GPR119 700/4885DDT 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.