Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285509 | 0.84 | CYP2C19 (0.50) | POLBMAPTMAPK1 | |
| SCHEMBL16664416 | 0.84 | MEN1 (0.46) | MTORKDM4EPOLBMAPTMAPK1 | |
| SCHEMBL30371733 | 0.80 | CNR2 (0.50) | CNR2HDAC4HDAC7HDAC5MEN1 | |
| SCHEMBL6366263 | 0.78 | HDAC4 (0.49) | CNR2HDAC4HDAC7HDAC5MEN1 | |
| SCHEMBL6366259 | 0.78 | HDAC4 (0.49) | CNR2HDAC4HDAC7HDAC5MEN1 | |
| SCHEMBL6366254 | 0.78 | HDAC4 (0.49) | CNR2HDAC4HDAC7HDAC5MEN1 | |
| SCHEMBL29421137 | 0.76 | AKR1C3 (0.51) | CNR2HDAC4HDAC7HDAC5CES2 | |
| SCHEMBL27953660 | 0.76 | MEN1 (0.48) | CNR2HDAC4HDAC7HDAC5POLB | |
| SCHEMBL2016833 | 0.76 | AKR1C3 (0.51) | CNR2HDAC4HDAC7HDAC5CES2 | |
| SCHEMBL2864430 | 0.76 | ROCK2 (0.49) | CNR2HDAC4HDAC7HDAC5CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | disclosed |