Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13282908 | 0.90 | NPSR1 (0.54) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13068697 | 0.88 | NPSR1 (0.68) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13282997 | 0.84 | NPSR1 (0.58) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13068698 | 0.84 | NPSR1 (0.66) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3379725 | 0.84 | NPSR1 (0.57) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13283009 | 0.83 | NPSR1 (0.57) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3376843 | 0.83 | NPSR1 (0.53) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13283003 | 0.83 | NPSR1 (0.56) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13282916 | 0.83 | NPSR1 (0.56) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3380682 | 0.81 | NPSR1 (0.56) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190746-A1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190746-A1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNK17, KCNQ2 | NPSR1 1722/4885CYP1A2 3034/4885CYP2C9 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.