Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378392 | 0.91 | NPSR1 (0.66) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13068698 | 0.90 | NPSR1 (0.66) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13282909 | 0.88 | NPSR1 (0.55) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13283029 | 0.85 | RAB9A (0.60) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13068744 | 0.84 | NPSR1 (0.67) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13282913 | 0.84 | NPSR1 (0.61) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13283035 | 0.84 | RAB9A (0.59) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13282908 | 0.82 | NPSR1 (0.54) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13282985 | 0.82 | NPSR1 (0.63) | NPSR1LMNARAB9AUSP2L3MBTL1 | |
| SCHEMBL13283031 | 0.81 | RAB9A (0.55) | NPSR1LMNARAB9AUSP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585522-B1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | ICAGEN INC (US) | 2010-11-17 | — | — | EP | disclosed |