Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283032 | 0.91 | L3MBTL1 (0.57) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13282985 | 0.90 | NPSR1 (0.63) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13068697 | 0.90 | NPSR1 (0.68) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13282912 | 0.87 | L3MBTL1 (0.65) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3380657 | 0.87 | NPSR1 (0.58) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13283030 | 0.85 | L3MBTL1 (0.63) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13282909 | 0.84 | NPSR1 (0.55) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13283031 | 0.84 | RAB9A (0.55) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL13068744 | 0.83 | NPSR1 (0.67) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3378392 | 0.82 | NPSR1 (0.66) | NPSR1RAB9AL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585522-B1 | QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS | ICAGEN INC (US) | 2010-11-17 | — | — | EP | disclosed |