Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104461 | 0.89 | SMARCA2 (0.46) | GRM5PRMT1RORC | |
| SCHEMBL106403 | 0.83 | RORC (0.39) | GRM5RORCNPC1ALDH1A1 | |
| SCHEMBL106404 | 0.83 | RORC (0.39) | GRM5RORCNPC1ALDH1A1 | |
| SCHEMBL105867 | 0.77 | TACR1 (0.45) | GRM5RORC | |
| SCHEMBL103004 | 0.75 | MAPT (0.49) | RORCALDH1A1LMNAENPP2 | |
| SCHEMBL168097 | 0.75 | SLC2A1 (0.44) | RORCKDM4E | |
| SCHEMBL3592710 | 0.75 | GRM5 (0.41) | GRM5RORCALDH1A1ENPP2 | |
| SCHEMBL168096 | 0.75 | SLC2A1 (0.44) | RORCKDM4E | |
| SCHEMBL103414 | 0.75 | GRM5 (0.41) | GRM5RORCALDH1A1ENPP2 | |
| SCHEMBL106246 | 0.73 | GPR119 (0.42) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-B1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | KOWA CO (JP) | 2013-11-06 | — | — | EP | disclosed |
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |