Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.81 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284350 | 1.00 | ADORA2A (0.81) | ADORA2ATLR8TLR7PDE4BRAB9A | |
| SCHEMBL1356263 | 0.89 | ADORA2A (1.00) | ADORA2ATLR8TLR7PDE4BRAB9A | |
| SCHEMBL1352825 | 0.89 | ADORA2A (1.00) | ADORA2ATLR8TLR7PDE4BRAB9A | |
| SCHEMBL8444460 | 0.82 | ADORA2A (0.78) | ADORA2A | |
| SCHEMBL8446498 | 0.81 | ADORA2A (0.80) | ADORA2A | |
| SCHEMBL8448329 | 0.81 | ADORA2A (0.80) | ADORA2A | |
| SCHEMBL13284477 | 0.79 | ADORA2A (0.69) | ADORA2A | |
| SCHEMBL1355638 | 0.77 | ADORA2A (0.73) | ADORA2APOLB | |
| SCHEMBL8444474 | 0.76 | ADORA2A (0.54) | ADORA2A | |
| SCHEMBL1355237 | 0.72 | ADORA2A (0.81) | ADORA2ARAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084425-A1 | NEW ADENOSINE RECEPTOR LIGANDS AND USES THEREOF | DOMAIN THERAPEUTICS (FR) | 2010-07-29 | — | — | WO | disclosed |