Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942535 | 0.81 | SLC7A5 (0.39) | CYP3A4SLC7A5 | |
| SCHEMBL13284690 | 0.79 | SLC7A5 (0.56) | ALDH1A1MEN1KMT2ACYP3A4SLC7A5 | |
| SCHEMBL93943 | 0.76 | CYP3A4 (0.65) | ALDH1A1MEN1KMT2ACYP3A4SLC7A5 | |
| SCHEMBL3393715 | 0.76 | CYP3A4 (0.65) | ALDH1A1MEN1KMT2ACYP3A4SLC7A5 | |
| Hydrochloric Acid SCHEMBL28535120 | 0.75 | CYP3A4 (0.63) | ALDH1A1MEN1KMT2ACYP3A4SLC7A5 | |
| Hydrochloric Acid SCHEMBL5491525 | 0.75 | CYP3A4 (0.63) | ALDH1A1MEN1KMT2ACYP3A4SLC7A5 | |
| Hydrochloric Acid SCHEMBL3393714 | 0.75 | CYP3A4 (0.63) | ALDH1A1MEN1KMT2ACYP3A4SLC7A5 | |
| SCHEMBL22445923 | 0.71 | POLB (0.33) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL21947598 | 0.70 | HSD17B10 (0.65) | ALDH1A1MEN1KMT2ASLC7A5SCN9A | |
| SCHEMBL7443089 | 0.70 | NAMPT (0.43) | ALDH1A1MEN1KMT2ASCN9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210882-A1 | Synthesis of new protected azahistidine, their processes and their use in synthesises | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081882-A2 | SYNTHESIS OF NEW PROTECTED AZAHISTIDINES, THEIR PROCESSES AND THEIR USE IN SYNTHESISES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2010-07-22 | — | — | WO | disclosed |