Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20502148 | 0.98 | HSD17B10 (0.63) | HSD17B10NLRP3LOXL2CPB2TPH1 | |
| SCHEMBL20543866 | 0.81 | FDPS (0.48) | CYP1A2CYP2C9PKMGAAKMT2A | |
| SCHEMBL21947585 | 0.81 | FDPS (0.48) | CYP1A2CYP2C9PKMGAAKMT2A | |
| SCHEMBL7337155 | 0.81 | FDPS (0.48) | CYP1A2CYP2C9PKMGAAKMT2A | |
| SCHEMBL7960935 | 0.80 | SLC7A5 (0.48) | CPB2TPH1MMP8PKMALPI | |
| Hydrochloric Acid SCHEMBL6980665 | 0.79 | FDPS (0.47) | CYP1A2CYP2C9PKMGAAKMT2A | |
| Hydrochloric Acid SCHEMBL29115298 | 0.79 | FDPS (0.47) | CYP1A2CYP2C9PKMGAAKMT2A | |
| Hydrochloric Acid SCHEMBL29115300 | 0.79 | FDPS (0.47) | CYP1A2CYP2C9PKMGAAKMT2A | |
| Hydrochloric Acid SCHEMBL29657240 | 0.79 | FDPS (0.47) | CYP1A2CYP2C9PKMGAAKMT2A | |
| SCHEMBL31000639 | 0.79 | HSD17B10 (1.00) | HSD17B10LOXL2TPH1CYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131141-A1 | CHEMICAL COMPOUNDS | IL1B, CASP1, IL1A | HSD17B10 1789/4885NLRP3 4/4885LOXL2 1288/4885 |
| US-11345669-B2 | Urea derivatives and methods of use thereof | IL1B, IL1A, NOD1 | HSD17B10 2652/4885NLRP3 5/4885LOXL2 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.