Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284661 | 0.86 | MET (0.57) | METNQO2 | |
| SCHEMBL13970438 | 0.85 | MET (0.55) | METNQO2 | |
| SCHEMBL15381974 | 0.85 | MET (0.62) | MET | |
| SCHEMBL3087804 | 0.85 | MET (0.74) | MET | |
| SCHEMBL15381973 | 0.85 | MET (0.55) | METNQO2 | |
| SCHEMBL3095671 | 0.83 | MET (0.81) | MET | |
| SCHEMBL13284451 | 0.83 | MET (0.59) | METNQO2 | |
| SCHEMBL3091003 | 0.83 | MET (0.67) | METNQO2 | |
| SCHEMBL2532298 | 0.82 | MET (0.58) | METNQO2 | |
| SCHEMBL28495299 | 0.82 | MET (0.51) | METMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010072296-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-07-01 | — | — | WO | disclosed |