Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.61 |
| ▸ | DRD2 | P14416 | 5/20 | 0.60 |
| ▸ | HTR2A | P28223 | 5/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | DRD4 | P21917 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.60 |
| ▸ | DRD1 | P21728 | 2/20 | 0.60 |
| ▸ | DRD5 | P21918 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285190 | 0.91 | DRD2 (0.74) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL3411659 | 0.91 | DRD2 (0.55) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL31098217 | 0.91 | DRD2 (0.74) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL2615198 | 0.91 | HRH4 (0.58) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL3411417 | 0.91 | DRD2 (0.63) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL2615197 | 0.91 | DRD2 (0.74) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL31098211 | 0.89 | HTR2C (0.53) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL3413775 | 0.82 | HTR2A (0.55) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL3414181 | 0.81 | DRD2 (0.60) | HRH4DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL3414295 | 0.81 | HRH4 (0.53) | HRH4DRD2HTR2AHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081036-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-15 | — | — | WO | disclosed |