Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285192 | 0.89 | HRH4 (0.61) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL31098236 | 0.87 | DRD2 (0.69) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL31098240 | 0.86 | HRH4 (0.69) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL3413799 | 0.86 | DRD2 (0.53) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL3405530 | 0.86 | DRD2 (0.61) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL3411659 | 0.84 | DRD2 (0.55) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL31098217 | 0.84 | DRD2 (0.74) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL13285190 | 0.84 | DRD2 (0.74) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL31098208 | 0.84 | DRD2 (0.64) | HTR2CDRD2HTR2ACHRM1HTR1A | |
| SCHEMBL3411417 | 0.83 | DRD2 (0.63) | HTR2CDRD2HTR2ACHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4428132-A1 | SLACK-ACTIVATING COMPOUNDS AND THEIR MEDICAL USE | Johann-Wolfgang-Goethe-Universität Frankfurt am Main (DE) | 2024-09-11 | — | — | EP | disclosed |