Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314645 | 0.84 | PTPN11 (0.43) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL24702521 | 0.81 | ALDH1A1 (0.46) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2090443 | 0.75 | PTPN11 (0.44) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL23367954 | 0.73 | APP (0.44) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL25382795 | 0.73 | SNCA (0.56) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL2090445 | 0.73 | APP (0.44) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL29183399 | 0.71 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHDAC1HDAC3 | |
| SCHEMBL14814605 | 0.70 | PTPN11 (0.42) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL14829437 | 0.69 | PTPN11 (0.41) | PTPN11KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL15356497 | 0.69 | PTPN11 (0.40) | PTPN11KDM4ENPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010080864-A1 | PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-07-15 | — | — | WO | disclosed |