Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314645 | 0.81 | PTPN11 (0.43) | ALDH1A1MAPTTDP1HDAC3HDAC4 | |
| SCHEMBL850770 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL16032766 | 0.81 | HDAC1 (0.48) | ALDH1A1MAPTTDP1HDAC3HDAC4 | |
| SCHEMBL29065959 | 0.81 | XDH (0.48) | ALDH1A1MAPTTDP1HDAC3HDAC4 | |
| SCHEMBL9394 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHDAC1HDAC6KDM4E | |
| SCHEMBL23146389 | 0.79 | CDC7 (0.45) | ALDH1A1MAPTTDP1HDAC3HDAC4 | |
| SCHEMBL8331915 | 0.77 | HDAC3 (0.61) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL23146302 | 0.77 | KDM4E (0.45) | ALDH1A1MAPTTDP1HDAC3HDAC4 | |
| SCHEMBL12151093 | 0.77 | NPC1 (0.40) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL1849553 | 0.77 | GAA (0.45) | ALDH1A1MAPTTDP1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285524-A | Substituted 4-amino isoindoline compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-12-26 | — | — | CN | disclosed |