Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 12/20 | 0.43 |
| ▸ | F2 | P00734 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259711 | 0.91 | PREP (0.43) | PREPF2 | |
| SCHEMBL13285547 | 0.78 | FAP (0.40) | PREP | |
| SCHEMBL12658549 | 0.76 | PREP (0.53) | PREPF2 | |
| SCHEMBL13285636 | 0.73 | — | — | |
| SCHEMBL13285633 | 0.71 | PREP (0.32) | PREP | |
| SCHEMBL12658545 | 0.70 | PREP (0.62) | PREPF2 | |
| SCHEMBL12658546 | 0.70 | PREP (0.44) | PREPF2 | |
| SCHEMBL19221608 | 0.70 | PREP (0.46) | PREPF2 | |
| SCHEMBL10022739 | 0.69 | PREP (0.67) | PREPF2 | |
| SCHEMBL25892010 | 0.69 | PREP (0.51) | PREPF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168032-A1 | Smart Pro-Drugs of Serine Protease Inhibitors | TRUSTEES OF TUFTS COLLEGE (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168032-A1 | Smart Pro-Drugs of Serine Protease Inhibitors | FAP, PREP, CTSC | PREP 2/4885F2 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.