Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 14/20 | 0.40 |
| ▸ | PREP | P48147 | 6/20 | 0.40 |
| ▸ | DPP4 | P27487 | 15/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.36 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259712 | 0.88 | FAP (0.39) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL13382231 | 0.83 | DPP4 (0.58) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL13285545 | 0.78 | PREP (0.43) | PREP | |
| SCHEMBL13285546 | 0.77 | ATM (0.47) | DPP4VHL | |
| SCHEMBL13285548 | 0.76 | ALDH1A1 (0.53) | DPP4 | |
| SCHEMBL15386487 | 0.72 | DPP4 (0.65) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL12658501 | 0.72 | DPP4 (0.65) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL13399328 | 0.72 | DPP4 (0.65) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL13285822 | 0.71 | DPP4 (0.64) | FAPPREPDPP4DPP7DPP8 | |
| SCHEMBL13399704 | 0.70 | ACE (0.43) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168032-A1 | Smart Pro-Drugs of Serine Protease Inhibitors | TRUSTEES OF TUFTS COLLEGE (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168032-A1 | Smart Pro-Drugs of Serine Protease Inhibitors | FAP, PREP, CTSC | FAP 1/4885PREP 2/4885DPP4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.