Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286492 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL13286279 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL13530964 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8350093 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL12463812 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL4653372 | 0.80 | CA12 (0.54) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL10792981 | 0.80 | ALDH1A1 (0.64) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13286329 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL13286282 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL17742794 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081731-A2 | DERIVATIVES OF SYRINGOLIN A | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) | 2010-07-22 | — | — | WO | disclosed |