Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286262 | 0.91 | PDK2 (0.40) | PDK2TLR9TLR8TLR7GYS1 | |
| SCHEMBL792216 | 0.88 | PDK2 (0.42) | PDK2GYS1 | |
| SCHEMBL13286175 | 0.84 | HSP90AA1 (0.48) | PDK2HPGD | |
| SCHEMBL13285989 | 0.83 | KMT2A (0.51) | ROCK2ROCK1HPGD | |
| SCHEMBL13286249 | 0.79 | CHEK2 (0.39) | — | |
| SCHEMBL791690 | 0.79 | PDK2 (0.40) | PDK2HDAC4 | |
| SCHEMBL792151 | 0.79 | ALDH1A1 (0.44) | PDK2HPGD | |
| SCHEMBL13285970 | 0.78 | MAPK14 (0.45) | PDK2ROCK2HPGDNAMPT | |
| SCHEMBL13285895 | 0.77 | SMN1; SMN2 (0.31) | DRD2 | |
| SCHEMBL13286253 | 0.77 | CYP3A4 (0.38) | ROCK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206715-A1 | Fused heterotetracyclic compounds and use thereof as hcv polymerase inhibitor | Japan Tobacco, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |