SCHEMBL1328626

SCHEMBL1328626

Cc1noc(C)c1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.46
MAPT P10636 8/20 0.46
MEN1 O00255 6/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
ALDH1A1 P00352 5/20 0.45
GPX4 P36969 1/20 0.45
SMN1; SMN2 Q16637 5/20 0.42
CASP3 P42574 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
LMNA P02545 3/20 0.40
HTT P42858 2/20 0.40
PABPC1 P11940 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
PKM P14618 1/20 0.38
ERN1 O75460 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27966691 0.98 KMT2A (0.45) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL2107620 0.78 PKM (0.44) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL28205712 0.78 ALDH1A1 (0.43) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL14977571 0.77 MAPT (0.57) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL14977572 0.77 MAPT (0.57) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL14986063 0.77 MAPT (0.57) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL6612124 0.75 MAPT (0.39) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL11524634 0.74 KMT2A (0.59) KMT2AMAPTMEN1RAB9AALDH1A1
SCHEMBL19893161 0.74 ALDH1A1 (0.57) KMT2AMAPTMEN1RAB9AALDH1A1
SCHEMBL18625799 0.74 MAPT (0.51) KMT2AMAPTMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478106-B Fluorescent sensor compound for detecting pH, and preparation and application thereof 山西大同大学 2024-11-22 CN claimed
CN-116478106-A Fluorescent sensor compound for detecting pH, and preparation and application thereof 山西大同大学 2023-07-25 CN claimed
CN-109503634-B Isoxazole derivative, synthesis method thereof and application of isoxazole derivative in detection of hydrogen sulfide 山西大学 2020-04-17 CN claimed
CN-104693194-A 3-(2-acrylate)-3'-nitroisoxazole oxoindole compound as well as preparation method and application thereof UNIV GUIZHOU 2015-06-10 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
CN-116478106-B Fluorescent sensor compound for detecting pH, and preparation and application thereof 山西大同大学 2024-11-22 CN disclosed
CN-116478106-B Fluorescent sensor compound for detecting pH, and preparation and application thereof 山西大同大学 2024-11-22 CN disclosed
CN-118459449-A Fluorescent probe with intramolecular charge transfer property and preparation method and application thereof 南方科技大学 2024-08-09 CN disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
EP-0034754-A1 2-((3-amino-2-hydroxy-propoxy)-styryl) isoxazoles, process for their preparation and pharmaceutical compositions containing them BASF Aktiengesellschaft (DE) 1981-09-02 EP disclosed