Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | ACACA | Q13085 | 4/20 | 0.33 |
| ▸ | ATF4 | P18848 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195197 | 1.00 | HTR2A (0.35) | HTR2ASLC6A4KCNH2CTSDBACE1 | |
| SCHEMBL10195199 | 0.89 | ALDH1A1 (0.37) | HTR2ASLC6A4KCNH2KDM4EALDH1A1 | |
| SCHEMBL13286427 | 0.89 | ALDH1A1 (0.37) | HTR2ASLC6A4KCNH2KDM4EALDH1A1 | |
| SCHEMBL16181160 | 0.89 | ALDH1A1 (0.35) | HTR2ASLC6A4KCNH2ACACBACACA | |
| SCHEMBL10195419 | 0.88 | LTB4R (0.33) | ALDH1A1 | |
| SCHEMBL10198860 | 0.88 | KDM4E (0.32) | KDM4EALDH1A1HPGDCHRNA3 | |
| SCHEMBL10195532 | 0.87 | CYP3A4 (0.33) | KDM4EALDH1A1HPGDHSD11B1 | |
| SCHEMBL16351665 | 0.86 | NR1I2 (0.41) | KDM4EALDH1A1HPGDHSD11B1 | |
| SCHEMBL10195198 | 0.86 | KDM4E (0.36) | HTR2ASLC6A4KCNH2HIF1AKDM4E | |
| SCHEMBL13286426 | 0.86 | KDM4E (0.36) | HTR2ASLC6A4KCNH2HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081755-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |