Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | CBR1 | P16152 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195004 | 1.00 | FFAR1 (0.37) | FFAR1HPGDKDM4EALDH1A1HTR2A | |
| SCHEMBL10195198 | 0.92 | KDM4E (0.36) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL13286426 | 0.92 | KDM4E (0.36) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL10195428 | 0.91 | HTR2A (0.33) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL10195199 | 0.89 | ALDH1A1 (0.37) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL13286427 | 0.89 | ALDH1A1 (0.37) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL10195531 | 0.89 | FFAR1 (0.40) | FFAR1HTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL16181160 | 0.85 | ALDH1A1 (0.35) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL10195197 | 0.85 | HTR2A (0.35) | HPGDKDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL13286405 | 0.85 | HTR2A (0.35) | HPGDKDM4EALDH1A1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081755-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |