Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | RAB9A | P51151 | 10/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 5/20 | 0.55 |
| ▸ | KDR | P35968 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GOT1 | P17174 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286648 | 0.85 | NPC1 (0.68) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286683 | 0.84 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286673 | 0.84 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286710 | 0.83 | EGFR (0.59) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286661 | 0.83 | RAB9A (0.82) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286743 | 0.83 | NPC1 (0.55) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286748 | 0.82 | MPO (0.54) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286675 | 0.81 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286746 | 0.80 | MPO (0.52) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13286677 | 0.80 | MPO (0.52) | NPC1RAB9AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728133-B2 | Stable pharmaceutical compositions | B&G PARTNERS LLC | 2010-06-01 | — | — | US | disclosed |