Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533861 | 0.98 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL34960 | 0.95 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL34880 | 0.89 | MEN1 (0.70) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL12864579 | 0.89 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL13041693 | 0.88 | NPBWR1 (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14193952 | 0.87 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL34856 | 0.86 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL22383437 | 0.86 | CHEK2 (0.60) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL13287104 | 0.86 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL13041694 | 0.86 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745030-B2 | Proton-conducting polymer membrane comprising sulfonic acid-containing polyazoles, and use thereof in fuel cells | BASF FUEL CELL GMBH (DE) | 2010-06-29 | — | — | US | disclosed |
| US-7649025-B2 | Composite ion-exchange membrane | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2010-01-19 | — | — | US | disclosed |
| US-7537852-B2 | Composite ion exchange membrane and electrolyte membrane electrode assembly | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2009-05-26 | — | — | US | disclosed |