⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053219 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL12400058 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL999206 | 0.69 | ALDH1A1 (0.40) | — | |
| SCHEMBL13312950 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL9289476 | 0.69 | CYP3A4 (0.50) | — | |
| SCHEMBL12383641 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL29953344 | 0.68 | KDM1A (0.35) | — | |
| SCHEMBL29353234 | 0.68 | ALDH1A1 (0.40) | — | |
| SCHEMBL6065091 | 0.68 | ALDH1A1 (0.40) | — | |
| SCHEMBL156826 | 0.67 | RAPGEF4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180062084-A1 | Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-03-01 | — | — | US | disclosed |
| US-20160372688-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20160257652-A1 | ANTIDIABETIC TRICYCLIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2016-09-08 | — | — | US | disclosed |
| US-9187408-B2 | Process for the preparation of protected L-alanine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2015-11-17 | — | — | US | disclosed |
| US-20140378701-A1 | PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-25 | — | — | US | disclosed |
| US-8853445-B2 | Process for the preparation of protected L-alanine derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-10-07 | — | — | US | disclosed |
| US-20140135525-A1 | PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-05-15 | — | — | US | disclosed |
| US-8710256-B2 | Process for the preparation of protected L-alanine derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-04-29 | — | — | US | disclosed |
| US-20100145090-A1 | PROCESS FOR THE PREPARATION OF PROTECTED L ALANINE DERIVATIVES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-06-10 | — | — | US | disclosed |