Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868376 | 0.84 | ADRB2 (0.53) | POLBALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL1495264 | 0.81 | FFAR1 (0.59) | LMNAL3MBTL1FFAR1 | |
| SCHEMBL19522848 | 0.80 | PCNA (0.52) | POLBALDH1A1KMT2APCNAGAA | |
| SCHEMBL14387746 | 0.79 | HDAC1 (0.53) | POLBALDH1A1PCNAHSD17B1HSD17B2 | |
| SCHEMBL11969671 | 0.78 | ACACB (0.65) | — | |
| SCHEMBL12228278 | 0.78 | F2RL1 (0.69) | POLBALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10138384 | 0.78 | PLK1 (0.51) | POLBALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL20382474 | 0.75 | LMNA (0.51) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL5889857 | 0.74 | ACACB (0.50) | POLBALDH1A1 | |
| SCHEMBL9155228 | 0.74 | CA12 (0.47) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158850-A1 | DENDRIMER BASED MODULAR PLATFORMS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158850-A1 | DENDRIMER BASED MODULAR PLATFORMS | ERBB2, ERBB3, ADGRE5 | POLB 3608/4885ALDH1A1 3681/4885KMT2A 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.