SCHEMBL13289031

SCHEMBL13289031

CN(c1ccc(-c2ccc(C3CCCC3)cc2)cc1)c1ccc(-c2ccc(C3CCCC3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.44
NOTUM Q6P988 3/20 0.42
KMT2A Q03164 2/20 0.41
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PSMB5 P28074 1/20 0.40
GALR1 P47211 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HRH4 Q9H3N8 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
S1PR1 P21453 2/20 0.36
LMNA P02545 2/20 0.36
S1PR5 Q9H228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20210323 0.92 SLC18A3 (0.46) SLC18A3NOTUMKMT2AHSP90AA1GAA
SCHEMBL10109506 0.91 MAPT (0.46) SLC18A3NOTUMKMT2AHSP90AA1GAA
SCHEMBL20210328 0.91 NPC1 (0.46) SLC18A3NOTUMKMT2AHSP90AA1GAA
SCHEMBL20800867 0.86 SLC18A3 (0.43) SLC18A3PSMB5SIGMAR1CYP2C9
SCHEMBL20800870 0.86 ALDH1A1 (0.46) SLC18A3KMT2AMAPTPSMB5ALDH1A1
SCHEMBL20800878 0.85 SLC18A3 (0.42) SLC18A3KMT2APSMB5ALDH1A1HDAC1
SCHEMBL20210022 0.85 LMNA (0.49) SLC18A3KMT2AMAPTPSMB5ALDH1A1
SCHEMBL10109191 0.85 SLC18A3 (0.43) SLC18A3MAPTPSMB5LMNASMN1; SMN2
SCHEMBL20800879 0.83 SLC18A3 (0.41) SLC18A3KMT2APSMB5ALDH1A1LMNA
SCHEMBL22453195 0.83 SLC18A3 (0.44) SLC18A3NOTUMKMT2AHSP90AA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010068000-A2 ARYL AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME 주식회사 두산 (KR) 2010-06-17 WO disclosed