SCHEMBL13290894

CC(=N)N1CCCN(C(=O)[C@@H](CNC(=N)N)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)Cc2ccccc2)CC1

nearest known ligand 0.57

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	OPRK1	P41145	15/20	0.57

▸	NPY4R	P50391	3/20	0.46

▸	NPY1R	P25929	2/20	0.46

▸	NPY2R	P49146	2/20	0.46

▸	NPY5R	Q15761	2/20	0.46

▸	OPRM1	P35372	1/20	0.45

▸	OPRD1	P41143	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10316406	0.95	OPRK1 (0.57)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL13290902	0.94	OPRK1 (0.59)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL13290914	0.92	OPRK1 (0.59)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL13290918	0.90	OPRK1 (0.62)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL13290888	0.90	OPRK1 (0.65)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL11927494	0.90	OPRK1 (0.55)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL11927495	0.90	OPRK1 (0.55)	OPRK1
SCHEMBL10316470	0.90	OPRK1 (0.55)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL18413053	0.90	OPRK1 (0.55)	OPRK1NPY4RNPY1RNPY2RNPY5R
SCHEMBL21886575	0.89	OPRK1 (0.51)	OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7727963-B2	Synthetic peptide amides	CARA THERAPEUTICS, INC. (US)	2010-06-01	—	—	US	disclosed