Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.59 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 3/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.47 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316406 | 0.94 | OPRK1 (0.57) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13290894 | 0.94 | OPRK1 (0.57) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL10316470 | 0.92 | OPRK1 (0.55) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11927494 | 0.92 | OPRK1 (0.55) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11927495 | 0.92 | OPRK1 (0.55) | OPRK1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL18413053 | 0.92 | OPRK1 (0.55) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21286534 | 0.91 | OPRK1 (0.61) | OPRK1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL12317858 | 0.90 | OPRK1 (0.58) | OPRK1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL13290871 | 0.90 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL10316467 | 0.89 | OPRK1 (0.76) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727963-B2 | Synthetic peptide amides | CARA THERAPEUTICS, INC. (US) | 2010-06-01 | — | — | US | disclosed |