Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13126350 | 0.86 | — | — | |
| SCHEMBL30177122 | 0.85 | DRD2 (0.32) | CNR2 | |
| SCHEMBL275480 | 0.85 | DRD2 (0.32) | CNR2 | |
| SCHEMBL3762745 | 0.84 | CNR2 (0.30) | CNR2 | |
| SCHEMBL13291365 | 0.83 | CNR1 (0.32) | CNR2CNR1MEN1ALDH1A1KMT2A | |
| SCHEMBL13383746 | 0.81 | TRPV1 (0.32) | — | |
| SCHEMBL30637698 | 0.80 | CNR1 (0.39) | CNR2CNR1MEN1ALDH1A1KMT2A | |
| SCHEMBL13291845 | 0.75 | NPC1 (0.31) | MEN1KMT2A | |
| SCHEMBL13291840 | 0.75 | DRD4 (0.32) | — | |
| SCHEMBL14767837 | 0.74 | IDH1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063422-A1 | SUBSTITUTED 1-(THIAZOLYL)- AND 1-(ISOTHIAZOLYL)PYRAZOLE-4-YL-ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010017923-A2 | HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-18 | — | — | WO | disclosed |
| WO-2009129953-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-10-29 | — | — | WO | disclosed |