Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291400 | 0.97 | CHRNA7 (0.55) | CHRNA7BCL2L1MCL1POLBSRD5A2 | |
| SCHEMBL13291402 | 0.97 | CHRNA7 (0.55) | CHRNA7BCL2L1MCL1POLBSRD5A2 | |
| SCHEMBL13291398 | 0.92 | ITGB1 (0.50) | BCL2L1POLBITGB1ITGA2CDC25B | |
| SCHEMBL13291401 | 0.90 | CHRNA7 (0.47) | CHRNA7BCL2L1MCL1POLBSRD5A2 | |
| SCHEMBL13291403 | 0.85 | MCL1 (0.44) | CHRNA7BCL2L1MCL1POLBHCRTR1 | |
| SCHEMBL8465626 | 0.82 | CYP2C9 (0.53) | BCL2L1HCRTR1HCRTR2CDC25BATM | |
| SCHEMBL13291426 | 0.81 | MMP2 (0.51) | CHRNA7BCL2L1ALDH1A1CYP2C9 | |
| SCHEMBL5959807 | 0.80 | CYP2C9 (0.58) | MCL1HCRTR1HCRTR2CDC25BATM | |
| SCHEMBL17668667 | 0.80 | BCL2L1 (0.55) | CHRNA7BCL2L1MCL1SRD5A2ALDH1A1 | |
| SCHEMBL13291420 | 0.80 | NPC1 (0.44) | CHRNA7BCL2L1ITGB1ITGA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727654-B2 | Membrane of a sulfonated aromatic polymers having polyphenyl and polyphenylene ether units with fluorine and nitrile groups; higher proton conductivity over a wide temperature range, and exhibits superior hot water resistance, chemical stability, toughness and mechanical strength | HONDA MOTOR CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |