Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAD | Q92934 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291399 | 0.92 | CHRNA7 (0.53) | ITGB1ITGA2CDC25BATMCYP2C9 | |
| SCHEMBL13291402 | 0.89 | CHRNA7 (0.55) | CYP2C8BCL2L1POLB | |
| SCHEMBL13291400 | 0.89 | CHRNA7 (0.55) | CYP2C8BCL2L1POLB | |
| SCHEMBL8465626 | 0.89 | CYP2C9 (0.53) | CDC25BATMCYP2C9CYP2C8BCL2L1 | |
| SCHEMBL13291426 | 0.88 | MMP2 (0.51) | CYP2C9BCL2L1BADMEN1KMT2A | |
| SCHEMBL5959807 | 0.87 | CYP2C9 (0.58) | CDC25BATMCYP2C9CYP2C8MEN1 | |
| SCHEMBL13291420 | 0.87 | NPC1 (0.44) | ITGB1ITGA2CYP2C9CYP2C8BCL2L1 | |
| SCHEMBL8465621 | 0.86 | CYP2C8 (0.53) | CYP2C9CYP2C8BCL2L1BADNPC1 | |
| SCHEMBL3296771 | 0.83 | BCL2L1 (0.65) | ITGB1ITGA2CDC25BATMBCL2L1 | |
| SCHEMBL10621680 | 0.83 | GSTA1 (0.64) | ITGB1ITGA2CDC25BATMBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727654-B2 | Membrane of a sulfonated aromatic polymers having polyphenyl and polyphenylene ether units with fluorine and nitrile groups; higher proton conductivity over a wide temperature range, and exhibits superior hot water resistance, chemical stability, toughness and mechanical strength | HONDA MOTOR CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |