Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13292093 | 0.87 | POLB (0.47) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL9675453 | 0.75 | FGFR1 (0.43) | POLBSMN1; SMN2LMNAHSD17B10NT5E | |
| SCHEMBL12526900 | 0.73 | PRKCA (0.41) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL22672647 | 0.73 | MEN1 (0.54) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL13487266 | 0.72 | ABL1 (0.38) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL16639110 | 0.72 | POLB (0.45) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL454099 | 0.71 | MAPT (0.50) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL27057456 | 0.71 | KMT2A (0.50) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL27056608 | 0.70 | KMT2A (0.47) | ABL1RIN1POLBSMN1; SMN2LMNA | |
| SCHEMBL27056601 | 0.70 | KMT2A (0.47) | ABL1RIN1POLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741297-B2 | Immunostimulatory, covalently lipidated oligonucleotides | ONCOTHYREON INC. (US) | 2010-06-22 | — | — | US | disclosed |