Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718481 | 0.78 | MAP3K5 (0.55) | POLBABL1RIN1KMT2AMEN1 | |
| SCHEMBL14037390 | 0.77 | POLB (0.41) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL15501179 | 0.76 | POLB (0.42) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL20051999 | 0.74 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL13292093 | 0.74 | POLB (0.47) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6055222 | 0.73 | ABL1 (0.52) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL16777754 | 0.72 | ABL1 (0.41) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL13292091 | 0.72 | ABL1 (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL6322275 | 0.71 | ABL1 (0.45) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14867647 | 0.71 | POLB (0.41) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190839-B1 | A PROCESS FOR CHIRAL RESOLUTION OF 2-SUBSTITUTED 4-SUBSTITUTED 1,3-OXATHIOLANES | AVEXA LTD (AU) | 2015-04-15 | — | — | EP | disclosed |