Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.77 |
| ▸ | DRD3 | P35462 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | APP | P05067 | 8/20 | 0.64 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.57 |
| ▸ | LOX | P28300 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edaravone SCHEMBL27972444 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL4704 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL28220108 | 0.86 | KMT2A (0.96) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL27849395 | 0.86 | KMT2A (0.96) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL27946869 | 0.86 | KMT2A (0.96) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL29109888 | 0.83 | KMT2A (0.90) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL12477822 | 0.80 | KMT2A (0.84) | KMT2AMAPTMEN1ALDH1A1GAA | |
| Edaravone SCHEMBL8083298 | 0.76 | MAPT (0.77) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL12756285 | 0.75 | MAPT (0.81) | KMT2AMAPTMEN1ALDH1A1GAA | |
| SCHEMBL28979899 | 0.75 | KMT2A (0.71) | KMT2AMAPTMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100150899-A1 | PYRAZOLINONE SCAVENGERS OF FREE RADICAL | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100150899-A1 | PYRAZOLINONE SCAVENGERS OF FREE RADICAL | GPX4, PRDX5, PRDX3 | KMT2A 4709/4885MAPT 3808/4885MEN1 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.