Edaravone

Edaravone

SCHEMBL4704

CC1=NN(c2ccccc2)C(=O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 1.00
MAPT P10636 5/20 1.00
MEN1 O00255 5/20 1.00
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
GAA P10253 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
CYP1A2 P05177 1/20 1.00
CHRM2 P08172 1/20 1.00
CYP3A4 P08684 1/20 1.00
CHRM1 P11229 1/20 1.00
TSHR P16473 1/20 1.00
PTGS1 P23219 1/20 1.00
DRD3 P35462 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
APP P05067 8/20 0.81
LMNA P02545 1/20 0.69
HTT P42858 1/20 0.69
RECQL P46063 1/20 0.67
SHMT2 P34897 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edaravone SCHEMBL27972444 1.00 KMT2A (1.00) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL28220108 0.98 KMT2A (0.96) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL27946869 0.98 KMT2A (0.96) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL27849395 0.98 KMT2A (0.96) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL29109888 0.95 KMT2A (0.90) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL12477822 0.92 KMT2A (0.84) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL8083298 0.87 MAPT (0.77) KMT2AMAPTMEN1ALDH1A1KDM4E
Edaravone SCHEMBL13292340 0.87 KMT2A (0.77) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL12756285 0.87 MAPT (0.81) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL2203669 0.86 MAPT (0.77) KMT2AMAPTMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12642 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144775-A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION OF EDARAVONE AND METHOD OF ADMINISTERING SAME K.K. BCJ-94 (JP) 2026-05-28 US claimed
US-20260146177-A1 ONE-STEP METHOD FOR MANUFACTURING AN INK COMPRISING AN N-TYPE CONDUCTING POLYMER WESTRA MATERIALS AB (SE) 2026-05-28 US claimed
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
US-20260138973-A1 SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
US-20260137680-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
EP-4744670-A1 POLYLACTIC ACID AND USE OF COPOLYMER THEREOF IN PREPARATION OF DRUG FOR PROMOTING NERVE GROWTH AND REPAIR Changchun Sinobiomaterials Co., Ltd. (CN) 2026-05-20 EP claimed
US-12629353-B2 Use of composition in treatment of cerebral stroke SIMCERE PHARMACEUTICAL CO., LTD. (CN) 2026-05-19 US claimed
CN-122063211-A Method for simultaneously detecting sodium bisulphite and cysteine hydrochloride and application thereof 九华华源药业股份有限公司 2026-05-19 CN claimed
EP-0410654-A2 Light- sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP claimed
EP-0378373-A2 Photohardenable compositions and their use in producing images THE MEAD CORPORATION (US) 1990-07-18 EP claimed
US-4927466-A AZO PIGMENTS PRODUCED BY REACTING AN AZO COMPOUND WITH A COUPLER IN THE PRESENCE OF A SURFACTANT BASF CORP. (US) 1990-05-22 US claimed
US-4857542-A INHIBITOR AGAINST LIPID PEROXIDATION MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-08-15 US claimed
EP-0208874-A1 Prophylactic and therapeutic agent for circulatory disorders MITSUBISHI KASEI CORPORATION (JP) 1987-01-21 EP claimed
US-4598033-A IMPROVED SENSITIVITY AND DURAVILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US claimed
US-4430420-A USING AN AMINOSULFONYLHYDRAZONE REDUCING AGENT EASTMAN KODAK COMPANY (US) 1984-02-07 US claimed
EP-0019219-B1 IMPROVED PHOTOIMAGING SYSTEMS WITH CYCLIC HYDRAZIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-06-22 EP claimed
US-4247618-A LEUCO DYES, PHOTOOXIDANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-27 US claimed
EP-0019219-A1 Improved photoimaging systems with cyclic hydrazides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-26 EP claimed