Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLI1 | P08151 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293138 | 0.92 | CES2 (0.56) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13293267 | 0.85 | USP2 (0.60) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13293260 | 0.82 | CES2 (0.70) | CES2CES1F3PTPN1USP2 | |
| SCHEMBL13293243 | 0.79 | EGLN2 (0.46) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13293272 | 0.79 | USP2 (0.61) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13910849 | 0.76 | PTPN1 (0.66) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13293192 | 0.76 | TOP2A (0.72) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13303949 | 0.76 | TOP2A (0.72) | CES2CES1F3SLC10A1PTPN1 | |
| SCHEMBL13293124 | 0.76 | TOP2A (0.65) | CES2CES1F3PTPN1TOP2A | |
| SCHEMBL12134029 | 0.75 | PTPN1 (0.70) | CES2CES1F3SLC10A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068668-A1 | 23-SUBSTITUTED DERIVATIVES OF LUPANE-TYPE PENTACYCLIC TRITERPENOIDS | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-17 | — | — | WO | disclosed |
| US-20100144688-A1 | 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100144688-A1 | 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids | ADVANCED LIFE SCIENCES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144688-A1 | 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids | BRCA1, PGF, LSS | CES2 4490/4885CES1 1204/4885F3 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.