Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16768644 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTR2ATAAR1CYP3A4TDP1 | |
| SCHEMBL13293275 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTR2ATAAR1CYP3A4TDP1 | |
| SCHEMBL16768626 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTR2ATAAR1CYP3A4TDP1 | |
| SCHEMBL16768646 | 1.00 | ALDH1A1 (0.33) | ALDH1A1HTR2ATAAR1CYP3A4TDP1 | |
| SCHEMBL15691877 | 0.89 | TAAR1 (0.31) | TAAR1 | |
| SCHEMBL16768615 | 0.81 | MTOR (0.30) | — | |
| SCHEMBL13293312 | 0.79 | ALDH1A1 (0.33) | ALDH1A1HTR2ATAAR1TDP1 | |
| SCHEMBL16768627 | 0.79 | — | — | |
| SCHEMBL18648384 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HTR2ATAAR1CYP3A4 | |
| SCHEMBL16768619 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716507-B2 | Iron(II) catalysts containing diimino-diphosphine tetradentate ligands and their synthesis | THE GOVERNING COUNCIL OF UNIVERSITY OF TORONTO (CA) | 2014-05-06 | — | — | US | disclosed |
| US-20100145087-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145087-A1 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS | FTH1, FECH, IDH1 | ALDH1A1 566/4885HTR2A 2069/4885TAAR1 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.