Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17814216 | 0.89 | DPP4 (0.55) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15087472 | 0.75 | DPP4 (0.41) | DPP4DPP7GLSCA12CA1 | |
| SCHEMBL10213727 | 0.75 | DPP4 (0.37) | DPP4DPP7GLSCA12CA1 | |
| SCHEMBL13259713 | 0.75 | DPP4 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15386492 | 0.75 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL13285826 | 0.75 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL29886476 | 0.74 | ALDH1A1 (0.55) | DPP4DPP7GLSCA12CA1 | |
| SCHEMBL13201866 | 0.73 | GLS (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14097634 | 0.73 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1174761 | 0.73 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727964-B2 | Peptidomimetic inhibitors of post-proline cleaving enzymes | TRUSTEES OF TUFTS COLLEGE (US) | 2010-06-01 | — | — | US | disclosed |