Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.70 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.70 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.70 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.70 |
| ▸ | ALB | P02768 | 1/20 | 0.70 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.70 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.70 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542423 | 0.92 | TTR (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL18613972 | 0.91 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL2881532 | 0.88 | TTR (0.59) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL15541968 | 0.87 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11817252 | 0.87 | TTR (0.58) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL8086145 | 0.86 | TTR (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL2889216 | 0.86 | TTR (0.57) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL21401012 | 0.86 | TTR (0.57) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL10801160 | 0.86 | TTR (0.57) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL15267398 | 0.86 | TTR (0.57) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | TTR 4167/4885CYP2C9 4025/4885USP2 4465/4885 |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | TTR 4167/4885CYP2C9 4025/4885USP2 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.