Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029495 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27842117 | 0.76 | KDM4E (0.38) | CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL26841600 | 0.76 | HDAC8 (0.31) | — | |
| SCHEMBL29005993 | 0.74 | KDM4E (0.37) | CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5018135 | 0.70 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL13993531 | 0.69 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10772034 | 0.68 | CNR2 (0.33) | CNR2 | |
| SCHEMBL155006 | 0.67 | — | — | |
| SCHEMBL21101112 | 0.64 | — | — | |
| SCHEMBL13594990 | 0.64 | CNR2 (0.36) | CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | CNR2 4734/4885ALDH1A1 4062/4885SMN1; SMN2 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.