Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670833 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL14538028 | 0.80 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL8624116 | 0.76 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL8271620 | 0.76 | LMNA (0.44) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL31608768 | 0.75 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL29558205 | 0.74 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL6578078 | 0.73 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL110764 | 0.73 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL226379 | 0.73 | ALDH1A1 (0.77) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL29832337 | 0.73 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CA2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193784-A1 | Cosmetic compositions containing an ester derivative of 2-pyrrolidinone 4-carboxy and a lipophilic triazine filter, with use of said derivative as a solvent of a lipophilic triazine filter | L'OREAL (FR) | 2010-06-09 | — | — | EP | disclosed |