Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543998 | 0.90 | PLA2G2A (0.50) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL2003959 | 0.90 | PLA2G2A (0.50) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL5444376 | 0.90 | PTGDR2 (0.58) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL2005905 | 0.89 | PLA2G2A (0.52) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL12255190 | 0.88 | PLA2G2A (0.55) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL5435406 | 0.88 | PLA2G2A (0.63) | PLA2G2APLA2G1BPTGDR2THRATHRB | |
| SCHEMBL2004754 | 0.87 | PPARG (0.56) | PLA2G2APLA2G1BPTGDR2ALOX5LMNA | |
| SCHEMBL2007815 | 0.86 | LMNA (0.58) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL2002065 | 0.86 | PTGDR2 (0.53) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 | |
| SCHEMBL2001190 | 0.85 | AKR1C3 (0.52) | PLA2G2APLA2G1BPTGDR2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062221-A1 | SUBSTITUTED 2-(5-HYDROXY-2-METHYL-1N-INDOLE-3-IL) ACETIC ACIDS AND ETHERS THEREOF AND THE USE OF SAME TO TREAT VIRAL DISEASES | АЛЛА XEM, ЛЛС (US) | 2010-06-03 | — | — | WO | disclosed |