SCHEMBL13299882

SCHEMBL13299882

CC(C)[C@H](NC(=O)C1CCCN1C(=O)[C@@H](NC(=O)CCCCCNC(=O)c1ccccn1)C(C)C)C(=O)c1nnc(C(C)(C)C)o1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299870 1.00 ELANE (0.47) ELANE
SCHEMBL13814745 0.94 ELANE (0.46) ELANE
SCHEMBL13299880 0.92 ELANE (0.43) ELANE
SCHEMBL13814744 0.92 ELANE (0.46) ELANE
SCHEMBL3255175 0.90 ELANE (0.48) ELANE
SCHEMBL13299875 0.90 ELANE (0.48) ELANE
SCHEMBL13299852 0.90 ELANE (0.43) ELANE
SCHEMBL13299866 0.90 ELANE (0.48) ELANE
Hydrochloric Acid SCHEMBL3249814 0.90 ELANE (0.47) ELANE
SCHEMBL13299864 0.88 ELANE (0.45) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010065461-A1 TRI-PEPTIDE INHIBITORS OF SERINE ELASTASES ACCUTHERA, INC. (US) 2010-06-10 WO disclosed
US-20090156509-A1 Tri-peptide Inhibitors of Serine Elastases ACCUTHERA, INC. (US) 2009-06-18 US disclosed
US-20090156509-A1 Tri-peptide Inhibitors of Serine Elastases ACCUTHERA, INC. (US) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156509-A1 Tri-peptide Inhibitors of Serine Elastases SCTR, CTRC, SERPINB1 ELANE 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.