Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861153 | 0.88 | VDR (0.47) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL14494394 | 0.83 | VDR (0.46) | VDR | |
| SCHEMBL14489178 | 0.82 | VDR (0.62) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL7156998 | 0.82 | VDR (0.62) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL8878792 | 0.82 | VDR (0.51) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL8880588 | 0.82 | VDR (0.51) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL9362341 | 0.82 | VDR (0.51) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL9361984 | 0.82 | VDR (0.51) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL8877053 | 0.82 | VDR (0.51) | VDRADRA1ANR1I2PGRADORA3 | |
| SCHEMBL7150345 | 0.81 | VDR (0.52) | VDRADRA1ANR1I2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010060197-A1 | METHOD FOR SYNTHESIZING VITAMIN D ANALOGS | CYTOCHROMA INC. (CA) | 2010-06-03 | — | — | WO | disclosed |