Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 10/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.57 |
| ▸ | TST | Q16762 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489178 | 1.00 | VDR (0.62) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL15081678 | 0.92 | VDR (0.62) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL15081679 | 0.92 | VDR (0.62) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL7151839 | 0.92 | VDR (0.58) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL7153800 | 0.92 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL9980582 | 0.92 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL9050757 | 0.92 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL9050754 | 0.92 | VDR (0.72) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL67867 | 0.90 | VDR (0.64) | VDRADRA1ALMNAABCB11AR | |
| SCHEMBL14364796 | 0.90 | VDR (0.64) | VDRADRA1ALMNAABCB11AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531459-B1 | Therapy of or prophylaxis against osteoporosis; generating new bone material; treating disease characterized by hyperproliferation and deficient cell differentiation | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-03-11 | — | — | US | disclosed |