Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.45 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228758 | 0.91 | CYP3A4 (0.51) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13301005 | 0.91 | CYP3A4 (0.51) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3226039 | 0.89 | CYP3A4 (0.47) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13301010 | 0.89 | CYP3A4 (0.47) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3331934 | 0.88 | CYP3A4 (0.48) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13301007 | 0.88 | CYP3A4 (0.48) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13300999 | 0.88 | CYP3A4 (0.56) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3336722 | 0.88 | CYP3A4 (0.56) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3228670 | 0.87 | CYP3A4 (0.49) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13300997 | 0.87 | CYP3A4 (0.49) | RAB9ACYP3A4CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CYP51A1, ERG28, CYP3A7 | RAB9A 2101/4885CYP3A4 7/4885CYP2C9 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.