SCHEMBL13301136

SCHEMBL13301136

NNC(=O)C(CCS)NC(=O)CS

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.34
ANPEP P15144 1/20 0.34
HIF1A Q16665 1/20 0.33
PTGS1 P23219 1/20 0.33
GSTK1 Q9Y2Q3 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GNPAT O15228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3331855 0.87 HIF1A (0.32) ENPEPHIF1APTGS1GSTK1CA1
SCHEMBL3326521 0.85 PTGS1 (0.37) ENPEPHIF1APTGS1GSTK1CA1
SCHEMBL13301149 0.81 FNTA (0.39) ENPEPGNPAT
SCHEMBL2992278 0.81 KDM4E (0.47) ENPEPANPEPHIF1ACA1CA2
SCHEMBL3328021 0.80 SIRT6 (0.40)
SCHEMBL929799 0.78 FOLH1 (0.44) PTGS1GSTK1CA2GNPAT
SCHEMBL929798 0.78 FOLH1 (0.44) PTGS1GSTK1CA2GNPAT
SCHEMBL8765134 0.78 FOLH1 (0.44) PTGS1GSTK1CA2GNPAT
SCHEMBL21980976 0.73 HIF1A (0.33) ENPEPANPEPHIF1ACA1CA2
SCHEMBL13301147 0.72 NOD1 (0.43) PTGS1GSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3095467-B1 ANTIBODY-ENZYME CONJUGATE VENTANA MED SYST INC (US) 2020-05-06 EP disclosed
EP-2963011-B1 MOLECULAR CONJUGATE VENTANA MED SYST INC (US) 2018-05-09 EP disclosed
EP-3095467-A1 MOLECULAR CONJUGATE Ventana Medical Systems, Inc. (US) 2016-11-23 EP disclosed
US-20160195540-A1 Molecular Conjugate VENTANA MED SYST INC (US) 2016-07-07 US disclosed
US-9310373-B2 Molecular conjugate VENTANA MEDICAL SYSTEMS, INC. (US) 2016-04-12 US disclosed
EP-2963011-A1 MOLECULAR CONJUGATE Ventana Medical Systems, Inc. (US) 2016-01-06 EP disclosed
US-20140205995-A1 MOLECULAR CONJUGATE VENTANA MEDICAL SYSTEMS, INC. (US) 2014-07-24 US disclosed
US-20100136652-A1 Molecular Conjugate VENTANA MEDICAL SYSTEMS, INC. 2010-06-03 US disclosed
US-20100136652-A1 Molecular Conjugate VENTANA MEDICAL SYSTEMS, INC. 2010-06-03 US disclosed
WO-2007062177-A2 MOLECULAR CONJUGATE VENTANA MEDICAL SYSTEMS, INC. (US) 2007-05-31 WO disclosed
US-20070117153-A1 Molecular conjugate VENTANA MEDICAL SYSTEMS, INC. 2007-05-24 US disclosed
US-20070117153-A1 Molecular conjugate VENTANA MEDICAL SYSTEMS, INC. 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160195540-A1 Molecular Conjugate CA12, FCGR2A, CA14 ENPEP 24/4885ANPEP 112/4885HIF1A 3349/4885
US-20100136652-A1 Molecular Conjugate CA12, FCGR2A, CA14 ENPEP 24/4885ANPEP 112/4885HIF1A 3349/4885
US-20070117153-A1 Molecular conjugate CA12, FCGR2A, CA14 ENPEP 24/4885ANPEP 112/4885HIF1A 3349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.